Xionglong/RFD4-Proteina

AI model by Xionglong

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Sequence and structure, designed together.Baker Lab × NVIDIA GenAIR Project page · Code · Documentation · Training data · Studio (ZeroGPU) · Studio (dedicated GPU) RFD4-Proteína is a flow-matching model for biomolecular design. It generates protein sequences and all-atom structures together, conditioned on the molecular context you want to preserve: a binding target, an enzyme motif, a ligand, or selected structural features. This repository is the canonical native bundle. config.json and model.safetensors at the root are the native weights, loaded by Proteina.frompretrained. It is one model throughout — nothing is retrained. The Diffusers weights are the same tensors re-prefixed and split across transformer/ and vae/. Diffusers needs modelindex.json at the root of whatever it is pointed at, so it has its own repository. Annotated-CIF preprocessing for Diffusers is in nvidia/RFD4-Proteina-prep. Training data lives in the companion dataset repository. The bundle includes both model components. Use the RFD4 loader below; this…

Xionglong/RFD4-Proteina on Hugging Face A short preview, not the full document.

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Inside the original model card — Document outline
  1. RFD4-Proteína
  2. Where to find each entry point
  3. At a glance
  4. Checkpoints in this release
  5. Start with one design
  6. 1. Install
  7. 2. Generate a small protein
  8. 3. Design a PD-L1 binder or an enzyme scaffold
  9. Loading the model
  10. Native RFD4 (this repository)
  11. Diffusers
  12. Compute presets

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Documentation belongs to its respective authors. Reported project/model license: bsd-3-clause. A listing is not a grant of reuse or training rights. Confirm the document’s own terms at the source.

Model overview

Xionglong/RFD4-Proteina is a task-unspecified model repository published by Xionglong on Hugging Face. The source reports the rfd4-proteina library.

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Model facts

Task
Not reported
Library
rfd4-proteina
Recent downloads (30 days)
0
Cumulative likes
0
Hugging Face trending score
0
Reported safetensors parameters
435,622,465
Architecture
Not reported
License
bsd-3-clause
Access
Not gated by Hugging Face
Created
2026-10-27T06:40:33.000Z
Last modified
2026-10-27T06:40:33.000Z

Compatibility and lineage

Reported languages: en

Base-model lineage was not included.

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Source: Hugging Face Hub. Metadata observed 2026-10-27T06:47:19.891Z. Daily imports are snapshots, not real-time monitoring.

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